Michael C Frühwald Selected Research

Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)

1/2019	Asparagine levels in the cerebrospinal fluid of children with acute lymphoblastic leukemia treated with pegylated-asparaginase in the induction phase of the AIEOP-BFM ALL 2009 study.
8/2010	Therapeutic drug monitoring of methotrexate in cerebrospinal fluid after systemic high-dose infusion in children: can the burden of intrathecal methotrexate be reduced?
6/2010	Validation of a predictive model for identifying an increased risk for thromboembolism in children with acute lymphoblastic leukemia: results of a multicenter cohort study.

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Michael C Frühwald Research Topics

Disease

49	Neoplasms (Cancer) 02/2024 - 01/2002
26	Rhabdoid Tumor (Rhabdoid Tumors) 02/2024 - 04/2007
7	Typical Teratoid Rhabdoid Tumor 01/2022 - 06/2011
5	Ependymoma 01/2021 - 05/2004
5	Medulloblastoma 01/2014 - 05/2004
4	Neoplasm Metastasis (Metastasis) 02/2024 - 09/2014
4	Brain Neoplasms (Brain Tumor) 02/2024 - 06/2011
4	Glioma (Gliomas) 01/2022 - 01/2009
4	Primitive Neuroectodermal Tumors (PNET) 02/2016 - 05/2004
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2019 - 06/2010
3	Neuroblastoma 02/2017 - 04/2007
3	Glioblastoma (Glioblastoma Multiforme) 01/2017 - 05/2004
3	Ewing Sarcoma (Sarcoma, Ewing) 09/2015 - 10/2012
3	Pathologic Complete Response 09/2014 - 12/2009
2	Carcinogenesis 01/2023 - 01/2020
2	Residual Neoplasm 12/2022 - 01/2021
2	Infections 01/2022 - 12/2008
2	Neuroectodermal Tumors (Neuroectodermal Tumor) 08/2013 - 12/2009
2	Osteosarcoma (Osteogenic Sarcoma) 01/2013 - 10/2012
1	Hydrocephalus (Hydrocephaly) 10/2023
1	monosomy Chromosome 7 01/2023
1	COVID-19 01/2022
1	Central Nervous System Neoplasms 01/2022
1	Li-Fraumeni Syndrome 01/2022
1	Adrenocortical Carcinoma 01/2022
1	Asymptomatic Infections 01/2022
1	Thyroid Neoplasms (Thyroid Cancer) 01/2022
1	Hematologic Neoplasms (Hematological Malignancy) 12/2021
1	Prostatic Neoplasms (Prostate Cancer) 12/2021
1	Rhabdoid Tumor Predisposition Syndrome 1 01/2021
1	Cardiotoxicity 01/2020
1	Leukemia 12/2019
1	Lymphoma (Lymphomas) 12/2019
1	Diffuse Intrinsic Pontine Glioma 01/2019
1	Thrombocytopenia (Thrombopenia) 10/2018
1	Nicolaides Baraitser syndrome 01/2018
1	KBG syndrome 01/2018
1	Coffin-Siris syndrome 01/2018

Drug/Important Bio-Agent (IBA)

14	Proteins (Proteins, Gene)FDA Link 01/2022 - 12/2009
5	DNA (Deoxyribonucleic Acid)IBA 10/2023 - 01/2002
5	Temozolomide (Temodar)FDA LinkGeneric 01/2021 - 01/2009
4	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020 - 06/2010
3	RNA (Ribonucleic Acid)IBA 01/2023 - 08/2012
3	NucleotidesIBA 01/2021 - 01/2018
3	Sucrose (Saccharose)IBA 01/2020 - 09/2014
3	Histone Deacetylase InhibitorsIBA 12/2019 - 04/2007
3	Vorinostat FDA Link 12/2019 - 04/2007
3	ChromatinIBA 01/2019 - 01/2012
3	Histones (Histone)IBA 11/2017 - 01/2003
3	hydrogen sulfite (bisulfite)IBA 03/2016 - 01/2009
3	Etoposide (VP 16)FDA LinkGeneric 09/2015 - 09/2007
2	Tyrosine (L-Tyrosine)FDA Link 01/2023 - 11/2010
2	Decitabine FDA Link 01/2022 - 12/2021
2	VaccinesIBA 01/2022 - 01/2016
2	SMARCB1 ProteinIBA 01/2021 - 09/2014
2	Asparaginase (Elspar)FDA Link 01/2019 - 06/2010
2	Cyclin D1IBA 01/2018 - 06/2010
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 05/2015 - 09/2007
2	Vincristine (Oncovin)FDA LinkGeneric 05/2015 - 09/2014
2	Antineoplastic Agents (Antineoplastics)IBA 03/2015 - 06/2010
2	AnthracyclinesIBA 09/2014 - 06/2010
2	Dactinomycin (Actinomycin)FDA LinkGeneric 09/2014 - 06/2010
2	Somatostatin Receptors (Somatostatin Receptor)IBA 08/2013 - 05/2004
2	Nonsense Codon (Nonsense Mutation)IBA 06/2011 - 02/2010
2	Adenosine Triphosphatases (ATPase)IBA 06/2011 - 02/2010
2	Methotrexate (Mexate)FDA LinkGeneric 08/2010 - 06/2010
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 10/2023
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2023
1	CPS 49IBA 04/2022
1	Immunoglobulin G (IgG)IBA 01/2022
1	Thyroglobulin FDA Link 01/2022
1	AntibodiesIBA 01/2022
1	Capsules (Microcapsules)IBA 01/2022
1	Mitotane (Lysodren)FDA Link 01/2022
1	SARS-CoV-2 spike proteinIBA 01/2022
1	ProteomeIBA 12/2021
1	Eosine Yellowish-(YS) (Eosin)IBA 01/2021
1	selinexorIBA 01/2021
1	DNA Transposable Elements (Element, IS)IBA 01/2021
1	Hematoxylin (Haematoxylon)IBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	AntigensIBA 01/2020
1	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 01/2020
1	dipinacoline glutamateIBA 01/2019
1	pegaspargase (Oncaspar)FDA Link 01/2019
1	AsparagineIBA 01/2019
1	Microfilament Proteins (Actin Binding Proteins)IBA 10/2018
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2018
1	LigandsIBA 01/2018

Therapy/Procedure

22	Therapeutics 01/2022 - 12/2009
10	Drug Therapy (Chemotherapy) 01/2023 - 01/2009
5	Radiotherapy 01/2024 - 05/2017
4	Ligation 10/2023 - 09/2014
3	Immunotherapy 11/2019 - 01/2016
2	Combined Modality Therapy 02/2024 - 06/2011
2	Investigational Therapies (Experimental Therapy) 10/2021 - 10/2013
2	Precision Medicine 01/2019 - 01/2016
1	Appendectomy 02/2024
1	Hematopoietic Stem Cell Transplantation 01/2023
1	Thyroidectomy 01/2022